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To date, the only human trial involving ipamorelin was just 7 days long [5], which is clearly insufficient to draw any conclusions about this peptide's long-term side effects

The analysis could be affected by residual confounding from unsupervised lifestyle modifications, and importantly, the reasons for treatment discontinuation were not recorded

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Int J Obes Suppl (2019) 9(1):6572

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Gynecomastia involves the growth of glandular breast tissue, which feels firm and rubbery, whereas pseudo gynecomastia is caused by excess fat, which feels soft and can be reduced through diet and exercise