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doi:10.4103/1319-3767.87176 Sachdeva S, Rawat AK, Reddy RS, Puri AS

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48 Eventually, Pol II dissociates from the promoter once the newly synthesized transcript is about 30 nucleotides

Because semaglutide has strong albumin binding, which leads to prolonged receptor activation, it may disturb the rhythmic calcium and cAMP cross-talk essential for normal salivary secretion