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While researchers note that the LD50 (lethal dose) for GHK-Cu in murine models equates to an impossibly massive single dose of roughly 23,000mg for a 70kg human adultrendering acute lethal toxicity highly improbable at the standard aesthetic therapeutic doses of 5-50mgthe long-term cumulative effects of daily copper peptide injections remain entirely unmapped in human populations

The pharmacologic inhibition of the xc antioxidant system improves the antitumor efficacy of COX inhibitors in the in vivo model of 3-MCA tumorigenesis