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We observed a delayed rise in BrAC and subjective effects in the GLP-1RA group as compared to controls, that was not explained by nausea

In contrast to MMNST, conventional MPNST usually arise from peripheral nerves or extraneural soft tissue and are commonly seen in neurofibromatosis type 1 (NF1) [2], while MMNST only rarely occurs in NF1 [10, 15]

None of the patients in the lotiglipron trials reported liver-related symptoms or side effects, there was no evidence of liver failure and none required treatment, Pfizer said

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