This steady activity helps maintain appetite suppression throughout most of the weekly dosing cycle
Arch Gynecol Obstet
These effects result from delayed gastric emptying and direct effects on the gastrointestinal tract
GLP-1 stands for Glucagon-Like Peptide-1, a hormone that your gut naturally produces
She has won Castle Conolly Top Doctor for several years in a row, among other prestigious awards

Kardie Tobb, DO, MS, FASPC, FACC, a boardcertified preventive cardiologist and the medical director for the Cone Health HeartCare Womens Heart Health and Cardio-Obstetrics Clinic, explains some of the most common reasons why GLP-1s may not deliver the results youre hoping for, including: You need a higher dose and have not yet reached a therapeutic dose as determined by your doctor High intake of liquid calories , including alcohol and ultra-processed foods Not getting enough protein , which can leave you persistently hungry and makes it harder to feel full Advanced diabetes or insulin resistance Taking other medications such as sulfonylureas, which lower blood sugar but can lead to weight gain Not adhering to your dosing schedule , such as inconsistent weekly injections or missed doses Differences in gut hormones or genetics And just because your GLP-1 isnt working immediately doesnt mean it wont work for you