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During post marketing surveillance, male infertility and/or poor seminal quality following treatment discontinuation have been reported

And all the drugs that work on this are targeting that receptor

[84] characterized the genome-wide DNA-binding sites of STAT3 factors upon the IL-10-induced anti-inflammatory response in mouse macrophages

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Repeated temperature cycling should be avoided, as moisture condensation on cold vials can initiate hydrolysis of amide and disulfide bonds