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Additionally, the nutritional composition of common foods is intricate, making it challenging to completely exclude the potential interference of various nutrients on the results, therefore the conclusion should be interpreted cautiously

Some may contain stimulants like caffeine or synephrine that can cause increased heart rate, anxiety, or sleep problems

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Data availability All data generated or analyzed during this study are included in the published article and Supplementary Information

Related clinical activity includes combination studies of YP05002 with its phase II-active glucose-dependent insulinotropic polypeptide receptor (GIPR) antagonist PF-07976016, alongside other small molecules

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