Separately, providers may prescribe compounded semaglutide or compounded tirzepatide, which are custom preparations filled through licensed compounding pharmacies rather than the standard branded supply chain
It was originally developed and FDA-approved as a diagnostic agent for assessing pituitary GH secretory capacity and was also used therapeutically for GH-deficient children
Lancet 14:110 Son JW, Kim S (2020) Comprehensive review of current and upcoming anti-obesity drugs
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Based on current clinical evidence, tirzepatide (Zepbound) produces the highest average weight loss, followed by semaglutide (Wegovy), and then liraglutide (Saxenda)
Seino Y, Fukushima M, Yabe D: GIP and GLP-1, the two incretin hormones: Similarities and differences