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in patients with stage 3 AKI undergoing 3 different RRT modalities, IHD, sustained low-efficiency diafiltration (SLEDf), and continuous venovenous hemofiltration (CVVH), demonstrated the highest amino acid loss for CVVH, followed by SLEDf and IHD

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Kidney metabolomic analysis revealed that FVP treatment inhibited ferroptosis by increasing glutathione (GSH), glutathione peroxidase 4 (GPX4), and solute carrier family 7 member 11 (SLC7A11) expression while reducing AA accumulation ( Figure 5 ) [192]