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In a clinical trial, participants taking Tirzepatide lost 15% of their body weight, on average

One of these studies initially found significant positive correlation between fasting ghrelin levels and activity in the left inferior occipital gyrus and right superior occipital gyrus, but these results did not survive outlier correction (Wever et al., 2021)

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Bedard PL, Davies MA, Kopetz S , Flaherty KT, Shapiro G, Luke JJ, Spreafico A, Wu B, Gomez C, Cartot-Cotton S, Mazuir F, Micallef S, Demers B, Juric D