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10.1038/s42255-023-00887-8 236 ZhangN.LinR.GaoW.XuH.LiY.HuangX.et al (2025)

At 10 nmol/l Ex-4 inhibits IB-phosphorylation and prevents NF-B/p65 nuclear translocation, halving tumor necrosis factor alpha (TNF-) and IL-6 both intracellularly and in the medium [19], thereby attenuating pro-inflammatory signaling and enhancing hMSC viability under inflammatory conditions