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761 The overexpression of CYP1B1 increases the ubiquitination and degradation of ACSL4, and melatonin could inhibit ferroptosis by regulating the ACSL4/CYP1B1 pathway, significantly reducing the cerebral ischemic area and neuron loss in MCAO mice

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Alternatively, diverse enzymes, such as papain lipase, lipase B from Candida ( C .) antarctica can also be employed (Caro et al

Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim S-H, et al

Thereby, BPC 157 was tested in rats subjected to cysteamine enema + colon-colon anastomosis colitis (9-11) and over-dose cuprizone application, a multiple sclerosis suited toxic experimental model (12)

These findings suggest that breathwork reduces oxidative stress by promoting the activity of endogenous antioxidant enzymes