Notoginsenoside Ft1 increases intracellular Ca accumulation, reduces 2+ cAMP levels by activating a signaling network mediated through P2Y receptors, and promotes platelet aggregation, thereby exerting a procoagulant effect
However, some studies have found a correlation between reduced NO synthesis due to decreased NOS activity and impaired wound healing when collagen deposition is reduced [134]
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Marazuela M, Garca-Lpez MA, Figueroa-Vega N, de la Fuente H, Alvarado-Snchez B, Monsivis-Urenda A, et al