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It's well known that some people taking Ozempic or similar medications may experience undesirable side effects alongside their weight loss, from facial skin sagging to the persistent stomach issues that Virta member Barbara encountered

Metabolic improvements (improved exercise recovery, reduced fatigue during activity) follow over 48 weeks

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The increase of FAO induced by butyrate in skeletal muscle may ascribe to the increased expression of PGC-1 (116)

Despite these findings and explicit advice against using GLP-1 agonist therapy in individuals with similar symptoms, Novo Nordisk failed to inform doctors about this potential issue or update their prescribing guidelines

Englot DJ, Chang EF, Auguste KI