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Patients prone to heart disease might fare best on medication that includes a GLP-1 component
Tirzepatide injections, used once weekly, operate by mimicking the effects of two hormones: GLP-1, which signals fullness to your brain, and GIP, which enhances sugar processing and insulin regulation
As a glucagon-like peptide-1 (GLP-1) receptor agonist, Liraglutide activates GLP-1 receptors, primarily found in pancreatic beta cells
Variation in MC4R , a melanocortin receptor central to satiety, together with FTO , GLP1R (the receptor these compounds target), and TCF7L2 (linked to glucose regulation), outlines your baseline metabolic terrain
Graphical abstract Access this article Similar content being viewed by others Availability of data and materials The datasets generated during and/or analyzed during the current study are available from the corresponding author on request