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GLP-1 agonists work by activating appetite-suppressing receptors and slowing gastric emptying, but repeated exposure can reduce the intensity of these signals

Author contributions AA: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

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Prescription medication is available only after consultation and approval by a licensed healthcare provider, if clinically appropriate, and approval through that evaluation is never guaranteed

Its important to note that Retatrutide is still in clinical trials and not yet approved for public use

Projecting the health and economic burden of cardiovascular disease among people with type 2 diabetes, 20222031