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Iron-driven oxidation of dopamine results in the generation of 6-OHDA, which specifically inhibits mitochondrial complexes I and IV, leading to mitochondrial dysfunction (120)

doi:10.1016/0272-0590(84)90138-6

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Grade A evidence includes multi-center cohort studies and meta-analyses with large sample sizes providing the strongest evidence base (81)

However, absence of documented interaction does not mean absence of risk when individual patient factorsgenetics, kidney function, and medication historyare considered

In short, they curb the users appetites so they eat less