Although we do not have clinical evidence regarding an impact on the effectiveness of oral contraceptives, there are some pharmacologic data to suggest that both tirzepatide (Mounjaro) and lixisenatide (Soliqua) may alter the absorption of oral contraceptives
Semaglutide works in the gut like the bodys natural GLP-1, slowing digestion, curbing hunger, and signaling fullness to the brain
Most guidelines support the use of metformin in people with an eGFR of 30 mL/min/1.73 m 2 or greater (although not at maximum recommended doses) and that there is a growing appreciation of temporarily withholding SGLT-2 inhibitors when patients are unwell or need to fast for a prolonged period of time to prevent the development of euglycaemic diabetic ketoacidosis
& Pearse, A
Available from: Zhang B, Cheng Z, Chen J, Zhang X, Liu D, Jiang H, et al
They are not equivalent to over-the-counter patches that rely on passive skin contact