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In prodrug systems, critical functional groups within drug scaffolds are well defined, typically involving a fixed molecular scaffold and a specific chemical bond linking the cargo to the triggering unit

Nrf2-regulated antioxidant response is activated by protein kinase C in postconditioned rat hearts

in addition, these diseased astrocytes demonstrate abnormal localisation of key astrocytic markers

PMID: 49 HodgkinsonKEl AbbarFDobranowskiPManoogianJButcherJFigeysDet al