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frontiersin.org STEP 1 semaglutide trial, New England Journal of Medicine (Wilding et al., 2021)

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Liraglutide activates the PKA/CREB pathway in the cartilage tissues of the knee OA rat model Western blot analysis was also used to detect the expression of PKA/CREB pathway components in the cartilage tissues of OA knees after treatment with liraglutide or saline