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Combined strategies involving controlled mechanical loading (exercise) followed by rest, along with glutathione optimization, have been associated with improved redox balance in joint tissues in animal models
Similarly, the involvement of oxidative stress in sepsis, which disrupts redox signaling, leading to molecular damage, has been highlighted (172)
Likewise, exosomes derived from stromal cells reinforce tumor progression by transporting growth signals and metabolic substrates, underscoring the bidirectional nature of EV-mediated communication within the TME (125)
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