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Changes in concentrations of creatine and related metabolites, as well as GSH and GSSG, and the activities of creatine- and GSH-forming enzymes in tissues of the HSB are summarized in Supplementary Tables S1, S2, S3, and S4

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Acetylcysteine Acetylcysteine still provides benefits, even if delayed until after hepatic failure has been established (~ 28% mortality benefit)

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