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doi:10.1111/bju.14399 4

But when the system becomes disruptedbecause of nutritional deficiencies, genetics, or oxidative stresshomocysteine begins to accumulate

In a frequently cited 1999 rat wound study in the Journal of Investigative Dermatology, topical Thymosin Beta-4 was associated with a 42% increase in reepithelialization at four days and as much as 61% at seven days compared with saline controls, alongside increased angiogenesis