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OGT is tyrosine-phosphorylated by the insulin receptor upon acute insulin stimulation and this phosphorylation increases the activity of the enzyme

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Fu Q, Shen S, Sun P, Gu Z, Bai Y, Wang X, et al

Obesity 15 , 11791186 (2007)

Valente MJ, Pelham WE, Smyth H, et al

We herein report a strategy to first form an intermediate with an adjacent, redox versatile SeN bond which undergoes two successive sigmatropic rearrangements to generate the para -amination product and regenerate the selenium catalyst (Fig