3 zeigt eine sicherlich weiterhin nicht vollstndige Liste weiterer Nebenwirkungen, die es in der Klinik zu beachten gilt (erweitert und adaptiert nach [5, 14])
Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae
To this end, we first abrogated phosphate conjugation by mutating the serine residue at the 114 position to an alanine (S114A) within the ectopically expressed NHR-49::YFP transgene
Excessive Fe 2+ can react with lipid radicals and H 2 O 2 to produce a large amount of reactive oxygen species (ROS), which can damage membrane lipids, proteins, DNA, and other biological macromolecules, causing ferroptosis ( 3.2 Glutathione metabolism and ferroptosis GPX4 is an antioxidant enzyme found in mammalian cells

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