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This work highlights a strategy of combinatorial peptide screening coupled with chemical exploration that could be used to generate novel agonists for other receptors with peptide ligands.

These drugs are homologous (53% and 97% respectively) to natural GLP-1, with the added benefit of resistance to degradation by DPP-4 which enhances their half-life

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People who have previously run GLP-1 based compounds and noticed post-cycle skin changes, either laxity or reduced firmness compared to their target weight look, are strong candidates for adding GHK-Cu to their next Retatrutide cycle

doi: 10.1007/BF03345571 5 ArthurJ