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Two compounds activating the same receptor create compounding risk without established benefit

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14,20 While the exact maximum dose has not been well defined, the American Association of Poison Control Centers (AAPCC) has recommended that regardless of the amount of drug ingested, a patient should be brought for medical evaluation if he or she displays signs or symptoms consistent with toxicity

JCI Insight 8 , e165566 (2023)

However, L-carnitine supplementation ameliorates the accumulation of long chain fatty acid around the mitochondria which could inhibit the mitochondrial membrane depolarization and permeability and ultimately suppresses the cells apoptosis [48, 49]