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Retroviruses , 1996, 12(14), 1373-1381

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

It has been proposed that PBMCs are sensitive to metabolic alterations in internal tissues, including the liver, and can have the capability to modulate their immunomodulatory properties in response to MASLD/MASH progression [43, 44, 107]

Changes in physical properties can cause lysosomal disruption through mechanical forces generated by crystals, leading to NLRP3 inflammasome activation

These linkages then interact with specific intrinsic changes at the pathological regions to ensure effective delivery or activation of the system for the application of interest

8 (4), 383395 (2006) F