53,54 However, it has also been suggested that the enhanced release of proinflammatory cytokines (TNF-, IL-1, IL-6, and IL-10) and chemokines (monocyte chemoattractant protein-1, macrophage inflammatory protein-2, and IL-8) further promotes hepatocyte damage, thereby aggravating necrosis
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Genetic Predispositions in Antioxidant and Detoxification Pathways Genetic variants affect enzyme activity in glutathione synthesis, recycling, and utilization
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