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Description

Glintborg D, Mumm H, Holst JJ, Andersen M

These drugs are collectively known as GLP-1 agonists because they mimic the bodys natural hormone GLP-1, which regulates appetite and digestion

13 (1), 13943 (2023) H

In the pancreas, GLP-1 stimulates post-prandial insulin secretion, promotes insulin biosynthesis, and improves insulin sensitivity

Tirzepatide represents a dual agonist, targeting both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, which may explain its enhanced efficacy in clinical trials