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For example, LC-based approaches can leverage a battery of orthogonal separation mechanisms (e.g., RPLC, HILIC, SEC, IEX), hyphenated to different detection systems (e.g., UV, ELSD, RI, MALS, MS) to expand the coverage of measurable properties

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coli showed total inactivation varying between 15 and 180 min (Wilks et al., 2005