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140 Scopoleitin mitigates APAP-induced hepatotoxicity through suppression of NLRP3 gene expression and concurrent inhibition of the Nrf2/HMGB1/TLR4/NF-B signaling pathway, resulting in reduced levels of proinflammatory factors

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Discovery of novel 1,3,8-Triazaspiro[4.5]decane derivatives that target the c subunit of F1/FO-adenosine triphosphate (ATP) synthase for the treatment of reperfusion damage in myocardial infarction

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67 To elaborate, the levels of GSH fall during apoptotic events in many cell types as a consequence of ROS, enhanced GSH efflux and decreased glutamate-cysteine ligase (GCL) activity

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