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Unlike stealth liposomes, which rely on the enhanced permeability and retention (EPR) effect for passive accumulation in diseased tissues, active targeting liposomes are functionalized with ligands that bind selectively to overexpressed receptors on target cells

This gets much worse with age, as the accumulation of toxins and cumulative damage of oxidative stress take their toll on the body

10.1093/humrep/dew360 87 IbrahimM

Reported activities include fibroblast stimulation, controlled intracellular copper delivery, modulation of collagen and glycosaminoglycan synthesis, and broad changes in gene expression across stress-response and tissue-repair networks

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