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By modulating the stress response, they could reduce the neuroimmune triggers that initiate psoriasis flares

The Ac-SDKP Fragment and Derivative Studies Beyond thymosin beta-4 and TB-500, the tetrapeptide fragment Ac-SDKP (acetyl-seryl-aspartyl-lysyl-proline), also known as goralatide, represents another bioactive derivative of the thymosin family

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About this article Cite this article Rukhsar, S., Usman, M., Yousaf, N

OASIS trials: establishing effective doses Phase 2 OASIS 1 findings: Tested multiple dose levels: 0.3mg, 0.6mg, 1.2mg, 2.4mg, 4.5mg weekly Duration: 26 weeks Primary endpoint: Weight loss at each dose Dose-response results: 0.3mg weekly: ~4% body weight loss 0.6mg weekly: ~6% body weight loss 1.2mg weekly: ~8% body weight loss 2.4mg weekly: ~10% body weight loss 4.5mg weekly: ~12% body weight loss Key insight: Clear dose-response relationship