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The medication is structurally modified to resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4) and includes an albumin-binding side chain, which extends its duration of action compared to native GLP-1

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Lowers blood sugar levels Helps regulate insulin and glucose, which can contribute to weight management

FIGURE 2 Liraglutide Alleviated Retinal Ganglion Cells Injuries by Weakening Mitophagy In Vitro To explore whether mitophagy played a role in high glucose-induced RGCs injury, we used TEM to observe autophagosome in cells directly

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for several indications: type 2 diabetes mellitus, chronic weight management, and more recently, to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and either overweight or obesity