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A shortage can lead to brittle nails, thinning hair, and changes in skin tone
doi:10.4239/wjd.v6.i14.1274 Minich DM, Brown BI
S.WangZ.CajkaT.BuffaJ
Tirzepatide, for example, activates receptors for a second hormone called GIP, and this is often cited as a potential explanation for its slightly superior efficacy over semaglutide, which acts on GLP-1 alone
Elevated GIP levels and duodenal K cell hyperplasia (62) have also been reported in HFD-treated mice, while Gipr deficiency protects mice from HFD-, leptin deficiency- or ovariectomy-induced weight gain (63, 64)
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