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Semaglutide and orforglipron act on the same single targetso this group may have maintained weight loss better after switching treatments, but they started with a less dramatic weight loss

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Because these drugs affect the central nervous system, mental-health outcomes are a foreseeable safety issue, even if the precise level of risk remains uncertain

It is not often that fans receive another chance to celebrate a sporting icon, and Craig Tileys successor at Tennis Australia, Andrew Abdo, will be desperate for Williams to play at Melbourne Park in January

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