Hepatology 2025;81:1595-1606
Tesamorelin's Phase 3 trials and Sermorelin's original approval studies were built around HIV-associated lipodystrophy and pediatric growth failure, not muscle building, so their bodybuilding use rests on extrapolation rather than direct testing
Anant Vinjamoori, chief medical officer of Hims, which plans to offer the peptides if the FDA does reclassify them
The goal is to maximize its regenerative and reparative benefits while minimizing any temporary adverse observations
Benefits May enhance lifespan, support immune function, regulate circadian rhythms, improve sleep quality, and promote cellular regeneration
It stimulates lipolysis (the breakdown of fat) and inhibits lipogenesis (the formation of new fat)