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Reduced Body Fat Storage: Increasing insulin secretion and reducing glucagon secretion, helps prevent excessive glucose availability for energy, which may decrease body fat storage

A formal allergy assessment by an immunologist or allergy specialist may be warranted in complex cases

TRIUMPH-5 is a comparator study in type 2 diabetes, benchmarking retatrutide against an active comparator rather than placebo

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Handle With Care Overall the risk of developing one of the conditions is low, at less than 1%

The benefits of triple agonism extended also to MASLD in a subgroup of 98 people, fat content normalised in approximately 90% of people receiving the highest retatrutide doses [82]