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The most common gallbladder problems associated with Zepbound are cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation)

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The S100 protein family interacts with specific target proteins to regulate cell proliferation, differentiation, migration, signal transduction, apoptosis, energy metastasis, and more ( Table 2 )

This research was financially supported by National Natural Science Foundation of China (81874255), Science and Technology Department of Sichuan Province (2021YJ0194, 2023JDRC0019, 2022ZYD0091) and Health Commission of Sichuan Province (21ZD008, 2023-802), Cadres Health Scientific Project of Sichuan Province (2021-803) and Sichuan Cancer Hospital Research Program (YB2023015, YBR2019003, YB2021023)

Its accelerating trajectory represents a major public health challenge and a leading cause of premature mortality

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