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Un complment contenant du glutathion oxyd (GSSG) oblige la cellule le rduire avant de pouvoir l'utiliser, ce qui consomme des ressources (NADPH) et limite l'intrt de la supplmentation
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However, a recent study has demonstrated that SDMA concentrations in patients with type 2 diabetes depend on glycaemic control
In contrast, mitochondrial PRDX3 undergoes hyperoxidation during lipid peroxidation stress and translocates to the plasma membrane, where it suppresses cystine uptake, depletes intracellular GSH, and amplifies ferroptotic execution 114
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doi: 10.2337/db22-0970 166
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