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doi: 10.1021/nn100713m 179 HillRPMacNeilSHaycockJW

Importantly, bempedoic acid is an inactive prodrug and requires activation by coenzyme A (CoA) with long-chain acyl-CoA 1 synthetase (ACSVL1), and the entire process takes place in the liver rather than in skeletal muscles, which from the very beginning indicated that it may be a very effective agent for statin-intolerant patients [216]

It belongs to a class of drugs called GLP-1 receptor agonists, which mimic a hormone naturally produced in the gut

Lipo-B injections are not recommended during pregnancy or while breastfeeding

Jia J, Wang N, Zheng Y, Mo X, Zhang Y, Ye S, et al