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It was originally developed to help reduce bleeding by preventing blood clots from breaking down

Metabolism of acetaminophen through the cytochrome P450 pathway results in production of N -acetyl- p -benzoquinone imine (NAPQI), the compound that damages the liver

Closely monitoring side effects and mood changes can help cue your healthcare team into the possible need to make adjustments to your care plan, adds Catanzano

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In the gastrointestinal tract, COX-1-derived prostaglandins function to increase production of the thick mucus/bicarbonate layer that coats gastric surfaces and buffers them against stomach acid (Vonkeman 2010)