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Stroke 23:13121317 Virmani MA, Caso V, Spadoni A, Rossi S, Russo F, Gaetani F (2001) The action of acetyl-l-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones

In the non-enzymatic pathway, the imbalance between redox systems triggers the process

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Notably, the peptide stimulates 59% of these genes while suppressing 41%, suggesting a sophisticated regulatory mechanism rather than a blunt biological effect