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12 Meanwhile, computational design approaches are accelerating the development of PROTACs and AUTACs, enabling targeted degradation of disease-associated proteins through UPS or autophagy, respectively

Unlike MSCs, which undergo senescence after a limited number of passages or with aging [59, 62], MSC-Exos do not exhibit signs of senescence and are more cost-effective and easier to produce at scale for clinical applications [63, 64]

Understanding the causes, symptoms, and treatment options for varicose veins is essential for effective management

381 In the CNS, ceruloplasmin is expressed almost exclusively in astrocytes, and its deficiency results in iron overload and formation of iron deposits

Although the tissues involved in tocochromanol catabolism are not well identified, CYP4F2 is expressed in liver and kidney (18), as well as intestine (19)

Tong SYC, Davis JS, Eichenberger E, Holland TL, Fowler VG