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Patients with a history of gallbladder disease can still be considered for semaglutide therapy but may require closer monitoring for symptoms of gallbladder issues

To extend the half-life of long-acting GLP-lRAs, various modifications have been made

Compounded GLP-1 medications are not recommended for patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2

Sometimes, this even shows up in bloodwork with low albumin levels

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Wang HL, Wei B, He HJ, Huang XR, Sheng JY, Chen XC, Wang L, Tan RZ, Li JC, Liu J, Yang SJ, Ma RC, Lan HY