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Furthermore, carotenoids can function as pro-oxidants by accelerating the radical chain reaction of lipid peroxidation in response to variations in oxygen pressure

The most one can say is mechanistic: raising GH and IGF-1 could, in principle, influence body composition and metabolism, and the animal models show effects on growth and body composition in a deficiency setting

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In the prefrontal cortex, increased TDO and KMO expression alongside reduced IDO and KAT shifts metabolism toward QA production, while cerebellar KYNA levels inversely correlate with symptom severity, linking KP dysfunction to 5-HT metabolism and clinical features [235]