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First interim results from FINE-REAL: a prospective, non-interventional, phase 4 study providing insights into the use and safety of finerenone in a routine clinical setting

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Mitochondria functional assays demonstrated that HC modulated OCR in manner comparable to the mitochondrial uncoupler FCCP, supporting the hypothesis that HC acts as a functional mitochondrial uncoupler, similarly to other anthraquinones (Simeone, 2025)

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