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Polypoid melanoma mainly affects young people (2039 years of age, [22]) and has a poor prognosis owing to a high incidence of ulceration and deep penetration reflected by a high Breslow index

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GLP-1 medications are generally contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and should be used cautiously with a history of pancreatitis

Most cases are temporary and resolve within 3 to 6 months once weight stabilizes