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With this compound, weight losses of up to 22% are generated in obese individuals [42], and several of the phase III SURPASS trials of patients with T2DM have shown reductions of HbA 1c to values at or below 5.7% (a completely normal value) in more than 50% of the patients, accompanied by weight losses in the order of 12% [43]

Niciu MJ, Ionescu DF, Mathews DC, Richards EM, Zarate CA

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HemeHPX uptake via TfR2, which is enriched on precursor red blood cells, may also occur during some stages of hemolysis

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hypersensitivity to any ingredient of the investigational drug or a history of allergic reactions